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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd45169c24df47725f252d88c09e4e1005331d317b74e5802d3dfd64802fd9a1d' 
  AND token = '6X9FOh4YbGbtZ6mc0cKEiFrOiQYfavOu67NftC4Uh0A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}