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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2fbe6370e4c6eb80a5bc3fe3aeeb622a1028adf11a4125eb32d16c3281d64a6b' 
  AND token = '2MjPh+EM93qvTMgxt+gCqK013SaVhs2lFIlI6vOi7EM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}