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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8a6efd9d5253e34294b8b8d44ca4f86f4ae2e8b2a4539d0d622ce1713e916d40' 
  AND token = 'ZTOs0bABAT94VUDm5H+XNme9G9KCMeKMEsCMTi1W378=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}