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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0044b85e130ffa2f7399a5a0f6df8c64cb9b7b5472f7ba50b798a186b3de78ff' 
  AND token = 'G63hO/G2q33hC8PnbPx1A01+lzI3AJj85LIA4kL6zro=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}