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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c617e2e77ee60362f7b2ae2f02978a5fe769ac0630e590dbba347f698c32c691' 
  AND token = 'IaH1xvnY1q1eOCTsVB2QDvEb1z4lC7DMoqGV45RAJ+4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}