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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0618bd05eaaeadfc4a4c5c598dc5e84af09aaf7e3f912658b493c6398d4d8c08' 
  AND token = 'tv0VOVv6zGBbRIbmnWjnYD8mixp3IlSOWkfRtgp3zgI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}