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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '45383d59b4f632c25baa53098c60e3e612c2a8acbdb48875b59ae279b5ebe0e5' 
  AND token = 'j4jle4dPhiApG3+K0Um9rPq1r9oBbFXiNfuxRpLOwdo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}