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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8d39cdab9a667bdfbbc271ff0b14cd9e64181207d422a421bc3251c59929d1e9' 
  AND token = '+zwONAj7fKaMaBO5HsSGAxac9JAJpjZ7Fk2MasJlBGQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}