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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '370772ea83e51196fce4f7b7f1210273a16d4fb76f6a210405a8371a397b08fd' 
  AND token = 'CVxH+2lkh2wrBfovfyf2HyA2k0DqqVHTi8BZTdnDBYs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}