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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5fdd2d664d89dc5c199a3b22d8ad3068afa80637fffa54a9f391e8dd8e75636f' 
  AND token = 't2qqU8/X4dcDFDQh/HN5o+ZSD9Mo9HXzmokAowcinUU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}