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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ab3057b5ac5c4285efc086ed611e459edbf3f0746192f51f549eabf1aa471e38' 
  AND token = 'DGGZ05G08QdZmgeQAA1a3vULXxvDhm9dC4ZehX8+7Oc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}