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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a06893ec8128c9a1c4f5bd3bce7c8b54b199c6ed4b0b57a30004bb122100d49f' 
  AND token = 'ec4Pio+7dFELLVmd6UojKwFaOShsGUF8gae7Y5gSFuc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}