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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0f758b602a429c0e315296751b15fa69085c4505bcee243f6763dc9cd899767b' 
  AND token = '5YXPE3F88zeZAHh6wHyMv/A0D//2AvhpAB38E2TGyDM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}