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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '72b8cfb475d4d0e071d1cb704b9b8c05f952b88445137fe55939a590997d6b88' 
  AND token = '1fvkchK+ZED5NNSZnLdBTpgbOpdHtSxE11pwmKNVIOI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}