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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '81fa8f4bea397d5adc52ab0b2e856dcdf1cd80c34115ac3ef130a5b86f3bd178' 
  AND token = 'XEFBZ7cpUJQlFgW/AXIKboDl3vKGB3kxhjU01lI7T60=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}