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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e1db1d209f08df3e65ec0cf1eeb0ee0ba979ca3d52b094f4064025b0e2f22b70' 
  AND token = 'cQysiVD57iJioDhHalwfQWrKmAlk8ZUuiT0T2YpC/tQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}