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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9e4d2ff6fd2198407583261c971d872aa49d30311a4c1071ece4e17776342cc5' 
  AND token = 'H21+RrS8DhJ/r7X4/mo2GHjV1cQaU5Amh9/UN16b9fg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}