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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '74a16254a65923c1c396f0d3fd6f796c5b001f9033037600e9e0dd61a2d4b496' 
  AND token = 'CnGe3cy1/db13dH1/Zj1xag/txwKD3f+UxzGUDov1LM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}