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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8b8e0bc84650796cb76cc2dac63f4dd5be8d92c8133ae0077657f61dc0a2cb19' 
  AND token = 'x49xxcMvJ5bSvfv0A0nyMaBHziMibfsoZ9d5r9irRGM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}