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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6bba269eb8b1213e8eec7eb9d4a21a34cc8f85130cd154f67a6a2177dc9187b6' 
  AND token = 'pChe5c3m1hs05ZBcI/KxTmuVW7mHgRbplokr7hiRdHo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}