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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '73009d2f68bb8fb1a97374208234a682ed308a559cc413f87a69bc2961a09cb2' 
  AND token = 'UA5qd4rcZgXFtOY6ipT5edjf3tdtBCXcNTjHoy3JFUQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}