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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd53d28c8893e5fe1dc7fc0bf5707fd69237691f499a114c4027a56070e00764a' 
  AND token = 'MUuipqi3CpEuMi9hEAOEPT9mM6o4Dqis5FEb8pn4VX4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}