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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b5a0f4963898b10edc494ee52337a7b74f261e35e6bd5b62add53d2518525842' 
  AND token = 'uaxSqo2kBx8MV6nbM0BCqXTnT3EXGxkP5uiUIwajxtE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}