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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2046f12fc81e4cf45ce372c6057f283a6c4b4e902cae2d4d1102244961c52e6e' 
  AND token = 'Z8MmaTICS1nASE4r7kdw5LK5RHhC3Jl3SkwxLQ2184M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}