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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '925c565ef26b5eeb5743ec2544c1b955e05985f8b3858e9bff71f9d475f6520d' 
  AND token = 'Skxc9SHAQW/RBbokE52PVJMrfM4MQy+oMlvK1im6WWU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}