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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '57959f448f82424bd89cd346ea12747c50544d8e98306095f9b5a3f53711bd2a' 
  AND token = 'hG87vcvl3mF1hWsrxhkcwrNXbh4e42Sh9ej0yffStVc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}