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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5f2d026e5d08b72979f96b4ef0cf38a6ea980a5e2192cbe57bff8382d916127d' 
  AND token = 'nbu2qmYXm45BjF7KO5rDiV1iRKaihdTqWXNUzl3duig=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}