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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '58e5baf5abe62ba8076e151d60fae60069aff73a30297ec7b4256f03b1f2d7ca' 
  AND token = '5mU/4vkT2nTmjAW+/qVGcMtE2+kzqWQ8DIwVL44ecWo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}