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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ddfded92bc6f05014c1943c89157a28351bb5cbfb44bff5d09fe6216f13852ef' 
  AND token = 'yQCTg2dvokKA1W5hDha7qmotFqF1ImHIlXjN4XNNlMc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}