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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'af55a36474171fdc7ffbb07405f77e5051e995a213544656a02713eca1b3363f' 
  AND token = 'rOdM2WG9RXWTZhWsyEd+mH9cblBIL6mk6045ow+mlpI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}