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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '250d35c34f272434885331bac28fae1a3c810ba812e9d9a9417ba9616b938213' 
  AND token = 'evTJAZDVMm+X0RV4upA5wV811CK6ya1rDrpwst25NwY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}