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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '10c67f8a05666ce42292791829a5092c7c04208872d626dd2649dab8008244dd' 
  AND token = 'ZhpKoN1TfwtWB8OMH6RbA0/vmkzLVCd5WMVXcnWQWxA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}