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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7cd0b93519e2461c6c186f736b30a57dac10f7e67a590e5aaa538d26eb3bca27' 
  AND token = 'zCVK4R1G+JdT2TdTmVtGBrFtzWNmxFRuyKFQrFwkSzo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}