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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7f801cf9325314cab2645c8e270b9872acd3e888759eec555833c2169a6c3787' 
  AND token = 'me0eLVXPQjCi0WdykkEUlJ2mraxv6w685eIPU6Aoo5Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}