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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b7591f6f42f8b103ba2d318e9bef15fa794816ec05684b066cb60bac8c80bcd2' 
  AND token = 'dWHpTt/EOcyxlqAwVaAfUvVcZn0JJTBEXfkqPf6c4KQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}