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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2273a4bafe52152acde403fcf27ca5969e483d702c00220d2b29fc05abf78d26' 
  AND token = 'Kx72Fjynne8ViAOWo3enn/FEh5HRFl/NhdfLkDxQl+8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}