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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '34b452dc2bf449cdd39961c29c413d8180f60a334fefcc8918a1824491c6089f' 
  AND token = '8UXCUxcfMGBbHH2phEcXrjjGvAiSKmsS1im0IFo5i8Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}