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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '91500a5d1eace94099b410dc2672e4545b02f4a99114e9bb07fea8fe63a9bcc1' 
  AND token = 'wjzlDl2Vlk8jSEgmwzMQbQZnIDlSfWP3h37BzuJwEpc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}