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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e67f276dbb3b721e83775c99e2cefb2e7fc596c5e48e379a1e04a6e98194caf3' 
  AND token = 'lmR3l53Y2Cv+O7quBQ4PKZqQLySp6aD12uvGH2NnKbo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}