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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8f5d3bc2c3329508fcba9a04cf27743f6be46e6dd54b1b61cc8aef214800bd7e' 
  AND token = 'fzGYHZe2Ztj1HtVHPS+v7PrF8ssePiKuxM7yo5BwtFE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}