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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c6c40ea47456131dcc0c2e5bd1306de6464a74a3cd05184b9a8dc77996e8e12f' 
  AND token = 'MJCOQAm/uzG0OvRjIeUyJEfNMnl79OsdWctDyF0gJIQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}