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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f16d55dfa699ac89fe346e9afafdfe129c66563f2afc74c7cd4f6c0f3c9bc94f' 
  AND token = 'lya02dKt9g30qpN24HCWhGxOMvvaE2qQz5gYKsDSnds=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}