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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5064e2e84f91a8e75920c4d70359a9e5e3e87b29d800ad4216119d4764d0d43f' 
  AND token = '9ZMjZ80SWBtMPg7NkZ4yrPb6/rXM8PQc7aHGk7BOuSI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}