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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4a359ccb6c3e90e586efbd766cb77f976ca6f40fe1a5b3b7e1bf204aefd9dc59' 
  AND token = 'aSMLF2Fm3CUN+2qeyxGL1XWY3NYvCk35Nb52F20uZ/k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}