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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a5ad816c47e0807e30a9ec396e73cfe1221aeb4d6475e535d0916776d2e00a65' 
  AND token = '1lyzdK7gRiBmnw8b2vOuz4h9x6RaMqftS61B73K3ChE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}