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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '202df9018ab9dd39964e0e860812857dfb6df1147edc5d1559c9324117f28c12' 
  AND token = 'OytnR6Mm4/zvJtt6JHlAWKRTiTu3C8k1A3iEjTg9RJ0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}