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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1335f15354bc670bfa2c14372fe5b33e624121f0c18ff83219e1bcbd5bcd3ab4' 
  AND token = 'laqXqcUMK2PgTncq1zZEGgoYppBLSipW199YHCKrMR0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}