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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6fdf03c54ec84252d5b3c5e91cca73cf7980348b84d08a0bfc89be59d54bf0a5' 
  AND token = 'bowfa9o/khMB0PGmhlH4AV5fIk0iv+jGItWKIFX7HDQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}