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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9b4783f13284db6c45a9bab43bd1e0d59dac85ca6f42be2b8b61248a01043db3' 
  AND token = 'dd0xqP/iOwon2yZx/km+v4t5vowvB/H+kAzFAk0migI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}