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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7b0281c608647c7b58beaabe5cb7777a61c7dac2d1a8fe6908009a51d112ea88' 
  AND token = 'UiXPnzwVsg6om1IF508juAlpNRx1mh3uzFGceVvzPZM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}